Instillation therapy for temporary replacement of the GAG layer in interstitial and chronic cystitis

Instillamed® is an innovative medical device by FARCO-PHARMA in the field of instillation therapy designed to restore the damaged protective layer of the bladder (GAG layer) on the bladder epithelium in interstitial and chronic cystitis.
Instillamed® contains the two natural active substances hyaluronic acid and chondroitin sulphate and is the therapy with two-component protection for the bladder wall.

Two-component protection: hyaluronic acid and chondroitin sulphate

The two components, hyaluronic acid and chondroitin sulphate, are natural components of the GAG layer. The components of the GAG layer that have been damaged in an inflammatory process can be rebuilt through substitution with Instillamed®. This enables intensive regeneration of the protective layer of the bladder.
In addition, the application of Instillamed® inhibits the accumulation of bacteria or immune complexes on the bladder wall. Instillamed® therefore restores the protective function of the bladder wall and is thereby able to reduce the risk of re-infection. At the same time, the hyaluronic acid increases the elasticity of the tissue and thereby combats fundamental, causal factors of chronic cystitis. Consequently, the regeneration of the GAG layer results in alleviation of the symptoms and improved quality of life for the patients.

Straightforward use thanks to sterile pre-filled syringe with safety adapter

To ensure that Instillamed® is as effective as possible, the solution is supplied in a ready-to-use, sterile pre-filled syringe with an accompanying safety adapter and is instilled directly into the bladder via a catheter. The sterile hyaluronic acid-chondroitin sulphate solution is slightly viscous; this consistency allows the instilled liquid to adhere to the bladder wall in an optimum manner and to exert its effect there during the exposure time of at least 30 minutes. The missing components, hyaluronic acid and chondroitin sulphate, are replaced during the Instillamed® exposure time. The longer Instillamed® can be left in the bladder, the more effective the regeneration of the inner protective layer.
The instillation is usually performed by a urologist. Patients who already have experience of self-catheterisation may also be able to perform the instillation themselves at home after consulting their doctor.

Sales unit

Instillamed® is a non-prescription medical device available only in pharmacies.


Fields of application

  • Interstitial cystitis
  • Chronic cystitis


  • Combination product of two natural components: hyaluronic acid and chondroitin sulphate
  • Intensive regeneration of the GAG layer
  • Reduces pain and urgency symptoms
  • Significantly fewer recurrent urinary tract infections
  • Straightforward use thanks to sterile pre-filled syringe + safety adapter